METTL14 downregulation drives S100A4+ monocyte-derived macrophages via MyD88/NF-κB pathway to promot...
METTL14 downregulation drives S100A4+ monocyte-derived macrophages via MyD88/NF-κB pathway to promote MAFLD progression
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Author / Creator
Wang, Yue-fan , Zhang, Wen-li , Li, Zhi-xuan , Liu, Yue , Tan, Jian , Yin, Hao-zan , Zhang, Zhi-chao , Piao, Xian-jie , Ruan, Min-hao , Dai, Zhi-hui , Wang, Si-jie , Mu, Chen-yang , Yuan, Ji-hang , Sun, Shu-han , Liu, Hui and Yang, Fu
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Without intervention, a considerable proportion of patients with metabolism‐associated fatty liver disease (MAFLD) will progress from simple steatosis to metabolism‐associated steatohepatitis (MASH), liver fibrosis, and even hepatocellular carcinoma. However, the molecular mechanisms that control progressive MAFLD have yet to be fully determined. H...
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Full title
METTL14 downregulation drives S100A4+ monocyte-derived macrophages via MyD88/NF-κB pathway to promote MAFLD progression
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TN_cdi_doaj_primary_oai_doaj_org_article_d334009046fa469e8ec41c2c5cd1cb6e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d334009046fa469e8ec41c2c5cd1cb6e
Other Identifiers
ISSN
2059-3635,2095-9907
E-ISSN
2059-3635
DOI
10.1038/s41392-024-01797-1
