International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-spe...
International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci
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Full title
Author / Creator
Klengel, Torsten , Chen, Chia-Yen , Choi, Karmel W. , Duncan, Laramie E. , Levey, Daniel F. , Logue, Mark W. , Polimanti, Renato , Provost, Allison C. , Ratanatharathorn, Andrew , Stein, Murray B. , Almli, Lynn M. , Amstadter, Ananda B. , Andreassen, Ole A. , Baker, Dewleen G. , Bierut, Laura J. , Bisson, Jonathan I. , Bolger, Elizabeth A. , Børglum, Anders D. , Brashear, Megan , Bryant, Richard A. , Bustamante, Angela C. , Bybjerg-Grauholm, Jonas , Calabrese, Joseph R. , Caldas- de- Almeida, José M. , Dale, Anders M. , Daly, Mark J. , Deckert, Jürgen , Delahanty, Douglas L. , Disner, Seth G. , Domschke, Katharina , Dzubur-Kulenovic, Alma , Farrer, Lindsay A. , Flory, Janine D. , Forbes, David , Galea, Sandro , Garrett, Melanie E. , Gillespie, Charles , Gordon, Scott D. , Guffanti, Guia , Hammamieh, Rasha , Harnal, Supriya , Hauser, Michael A. , Heath, Andrew C. , Hemmings, Sian M. J. , Jett, Marti , Jones, Ian , Qin, Xue-Jun , Junglen, Angela G. , Kessler, Ronald C. , Kimbrel, Nathan A. , Koen, Nastassja , Kranzler, Henry R. , Kremen, William S. , Lawford, Bruce R. , Lebois, Lauren A. M. , Linnstaedt, Sarah D. , Lugonja, Bozo , Maples-Keller, Jessica , Martin, Nicholas G. , Mavissakalian, Matig R. , McFarlane, Alexander , McGlinchey, Regina E. , McLaughlin, Katie A. , Mehta, Divya , Milberg, William P. , Miller, Mark W. , Morey, Rajendra A. , Morris, Charles Phillip , Mors, Ole , Mortensen, Preben B. , Neale, Benjamin M. , Nelson, Elliot C. , Orcutt, Holly K. , Panizzon, Matthew S. , Peverill, Matthew , Pietrzak, Robert H. , Polusny, Melissa A. , Risbrough, Victoria B. , Rothbaum, Alex O. , Ruggiero, Ken , Rung, Ariane , Rutten, Bart P. F. , Sheerin, Christina M. , Sponheim, Scott R. , Stein, Dan J. , Stevens, Jennifer S. , Teicher, Martin H. , Trapido, Edward , Ursano, Robert J. , Vermetten, Eric , Vinkers, Christiaan H. , Williams, Michelle A. , Williamson, Douglas E. , Winternitz, Sherry , Wolf, Christiane , Yehuda, Rachel , Young, Keith A. , Zhao, Hongyu , Liberzon, Israel and Ressler, Kerry J.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
The risk of posttraumatic stress disorder (PTSD) following trauma is heritable, but robust common variants have yet to be identified. In a multi-ethnic cohort including over 30,000 PTSD cases and 170,000 controls we conduct a genome-wide association study of PTSD. We demonstrate SNP-based heritability estimates of 5–20%, varying by sex. Three genom...
Alternative Titles
Full title
International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci
Authors, Artists and Contributors
Author / Creator
Chen, Chia-Yen
Choi, Karmel W.
Duncan, Laramie E.
Levey, Daniel F.
Logue, Mark W.
Polimanti, Renato
Provost, Allison C.
Ratanatharathorn, Andrew
Stein, Murray B.
Almli, Lynn M.
Amstadter, Ananda B.
Andreassen, Ole A.
Baker, Dewleen G.
Bierut, Laura J.
Bisson, Jonathan I.
Bolger, Elizabeth A.
Børglum, Anders D.
Brashear, Megan
Bryant, Richard A.
Bustamante, Angela C.
Bybjerg-Grauholm, Jonas
Calabrese, Joseph R.
Caldas- de- Almeida, José M.
Dale, Anders M.
Daly, Mark J.
Deckert, Jürgen
Delahanty, Douglas L.
Disner, Seth G.
Domschke, Katharina
Dzubur-Kulenovic, Alma
Farrer, Lindsay A.
Flory, Janine D.
Forbes, David
Galea, Sandro
Garrett, Melanie E.
Gillespie, Charles
Gordon, Scott D.
Guffanti, Guia
Hammamieh, Rasha
Harnal, Supriya
Hauser, Michael A.
Heath, Andrew C.
Hemmings, Sian M. J.
Jett, Marti
Jones, Ian
Qin, Xue-Jun
Junglen, Angela G.
Kessler, Ronald C.
Kimbrel, Nathan A.
Koen, Nastassja
Kranzler, Henry R.
Kremen, William S.
Lawford, Bruce R.
Lebois, Lauren A. M.
Linnstaedt, Sarah D.
Lugonja, Bozo
Maples-Keller, Jessica
Martin, Nicholas G.
Mavissakalian, Matig R.
McFarlane, Alexander
McGlinchey, Regina E.
McLaughlin, Katie A.
Mehta, Divya
Milberg, William P.
Miller, Mark W.
Morey, Rajendra A.
Morris, Charles Phillip
Mors, Ole
Mortensen, Preben B.
Neale, Benjamin M.
Nelson, Elliot C.
Orcutt, Holly K.
Panizzon, Matthew S.
Peverill, Matthew
Pietrzak, Robert H.
Polusny, Melissa A.
Risbrough, Victoria B.
Rothbaum, Alex O.
Ruggiero, Ken
Rung, Ariane
Rutten, Bart P. F.
Sheerin, Christina M.
Sponheim, Scott R.
Stein, Dan J.
Stevens, Jennifer S.
Teicher, Martin H.
Trapido, Edward
Ursano, Robert J.
Vermetten, Eric
Vinkers, Christiaan H.
Williams, Michelle A.
Williamson, Douglas E.
Winternitz, Sherry
Wolf, Christiane
Yehuda, Rachel
Young, Keith A.
Zhao, Hongyu
Liberzon, Israel
Ressler, Kerry J.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_d39ff05b76b746a5b312681b5db7b9fc
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d39ff05b76b746a5b312681b5db7b9fc
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-12576-w
