Cell-specific expression of key mitochondrial enzymes limits OXPHOS in astrocytes of the adult human...
Cell-specific expression of key mitochondrial enzymes limits OXPHOS in astrocytes of the adult human neocortex and hippocampal formation
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The astrocyte-to-neuron lactate shuttle model entails that, upon glutamatergic neurotransmission, glycolytically derived pyruvate in astrocytes is mainly converted to lactate instead of being entirely catabolized in mitochondria. The mechanism of this metabolic rewiring and its occurrence in human brain are unclear. Here by using immunohistochemist...
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Cell-specific expression of key mitochondrial enzymes limits OXPHOS in astrocytes of the adult human neocortex and hippocampal formation
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TN_cdi_doaj_primary_oai_doaj_org_article_d47b2b71158e40009605bff1a4f8f169
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d47b2b71158e40009605bff1a4f8f169
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ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-024-06751-z
