Circuit-specific hippocampal ΔFosB underlies resilience to stress-induced social avoidance
Circuit-specific hippocampal ΔFosB underlies resilience to stress-induced social avoidance
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Author / Creator
Eagle, Andrew L. , Manning, Claire E. , Williams, Elizabeth S. , Bastle, Ryan M. , Gajewski, Paula A. , Garrison, Amber , Wirtz, Alexis J. , Akguen, Seda , Brandel-Ankrapp, Katie , Endege, Wilson , Boyce, Frederick M. , Ohnishi, Yoshinori N. , Mazei-Robison, Michelle , Maze, Ian , Neve, Rachel L. and Robison, Alfred J.
Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Chronic stress is a key risk factor for mood disorders like depression, but the stress-induced changes in brain circuit function and gene expression underlying depression symptoms are not completely understood, hindering development of novel treatments. Because of its projections to brain regions regulating reward and anxiety, the ventral hippocamp...
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Full title
Circuit-specific hippocampal ΔFosB underlies resilience to stress-induced social avoidance
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TN_cdi_doaj_primary_oai_doaj_org_article_d4b95067e74845b094227a1938275611
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d4b95067e74845b094227a1938275611
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-17825-x
