Lipidic folding pathway of α-Synuclein via a toxic oligomer
Lipidic folding pathway of α-Synuclein via a toxic oligomer
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Aggregation intermediates play a pivotal role in the assembly of amyloid fibrils, which are central to the pathogenesis of neurodegenerative diseases. The structures of filamentous intermediates and mature fibrils are now efficiently determined by single-particle cryo-electron microscopy. By contrast, smaller pre-fibrillar α-Synuclein (αS) oligomer...
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Lipidic folding pathway of α-Synuclein via a toxic oligomer
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TN_cdi_doaj_primary_oai_doaj_org_article_d4bd70c5c1a24f03bdfefd37f570651a
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d4bd70c5c1a24f03bdfefd37f570651a
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-025-55849-3
