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Integrated systems modeling of severe asthma: Exploration of IL‐33/ST2 antagonism

Integrated systems modeling of severe asthma: Exploration of IL‐33/ST2 antagonism

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d4c73fd7fc9c4dc591d8ab594626b323

Integrated systems modeling of severe asthma: Exploration of IL‐33/ST2 antagonism

About this item

Full title

Integrated systems modeling of severe asthma: Exploration of IL‐33/ST2 antagonism

Publisher

Hoboken: John Wiley & Sons, Inc

Journal title

CPT: Pharmacometrics & Systems Pharmacology, 2022-09, Vol.11 (9), p.1268-1277

Language

English

Formats

Publication information

Publisher

Hoboken: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Asthma is a complex, heterogeneous disease with a high unmet medical need, despite therapies targeting a multitude of pathways. The ability to quantitatively integrate preclinical and clinical data on these pathways could aid in the development and testing of novel targets and therapeutics. In this work, we develop a computational model of asthma b...

Alternative Titles

Full title

Integrated systems modeling of severe asthma: Exploration of IL‐33/ST2 antagonism

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_d4c73fd7fc9c4dc591d8ab594626b323

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d4c73fd7fc9c4dc591d8ab594626b323

Other Identifiers

ISSN

2163-8306

E-ISSN

2163-8306

DOI

10.1002/psp4.12842

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