Cryo-EM structure of TFIIH/Rad4–Rad23–Rad33 in damaged DNA opening in nucleotide excision repair
Cryo-EM structure of TFIIH/Rad4–Rad23–Rad33 in damaged DNA opening in nucleotide excision repair
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The versatile nucleotide excision repair (NER) pathway initiates as the XPC–RAD23B–CETN2 complex first recognizes DNA lesions from the genomic DNA and recruits the general transcription factor complex, TFIIH, for subsequent lesion verification. Here, we present a cryo-EM structure of an NER initiation complex containing Rad4–Rad23-Rad33 (yeast homo...
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Cryo-EM structure of TFIIH/Rad4–Rad23–Rad33 in damaged DNA opening in nucleotide excision repair
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TN_cdi_doaj_primary_oai_doaj_org_article_d50d4da2dfcb426987c2cc95413c64ea
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d50d4da2dfcb426987c2cc95413c64ea
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-23684-x
