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Energy stress-induced lncRNA FILNC1 represses c-Myc-mediated energy metabolism and inhibits renal tu...

Energy stress-induced lncRNA FILNC1 represses c-Myc-mediated energy metabolism and inhibits renal tu...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d52cbc814c434f93b3293211e3737a33

Energy stress-induced lncRNA FILNC1 represses c-Myc-mediated energy metabolism and inhibits renal tumor development

About this item

Full title

Energy stress-induced lncRNA FILNC1 represses c-Myc-mediated energy metabolism and inhibits renal tumor development

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2017-10, Vol.8 (1), p.783-13, Article 783

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The roles of long non-coding RNAs in cancer metabolism remain largely unexplored. Here we identify
FILNC1
(FoxO-induced long non-coding RNA 1) as an energy stress-induced long non-coding RNA by FoxO transcription factors.
FILNC1
deficiency in renal cancer cells alleviates energy stress-induced apoptosis and markedly promotes renal tumor...

Alternative Titles

Full title

Energy stress-induced lncRNA FILNC1 represses c-Myc-mediated energy metabolism and inhibits renal tumor development

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_d52cbc814c434f93b3293211e3737a33

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d52cbc814c434f93b3293211e3737a33

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-017-00902-z

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