Origin of a folded repeat protein from an intrinsically disordered ancestor
Origin of a folded repeat protein from an intrinsically disordered ancestor
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England: eLife Sciences Publications Ltd
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English
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England: eLife Sciences Publications Ltd
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Repetitive proteins are thought to have arisen through the amplification of subdomain-sized peptides. Many of these originated in a non-repetitive context as cofactors of RNA-based replication and catalysis, and required the RNA to assume their active conformation. In search of the origins of one of the most widespread repeat protein families, the...
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Origin of a folded repeat protein from an intrinsically disordered ancestor
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TN_cdi_doaj_primary_oai_doaj_org_article_d57468ded49c43f38933248a52e54212
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d57468ded49c43f38933248a52e54212
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.16761