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The cryo-EM structure of the bd oxidase from M. tuberculosis reveals a unique structural framework a...

The cryo-EM structure of the bd oxidase from M. tuberculosis reveals a unique structural framework a...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d59d3dd24560451195a1764a95c9ea6d

The cryo-EM structure of the bd oxidase from M. tuberculosis reveals a unique structural framework and enables rational drug design to combat TB

About this item

Full title

The cryo-EM structure of the bd oxidase from M. tuberculosis reveals a unique structural framework and enables rational drug design to combat TB

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2021-09, Vol.12 (1), p.5236-5236, Article 5236

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

New drugs are urgently needed to combat the global TB epidemic. Targeting simultaneously multiple respiratory enzyme complexes of
Mycobacterium tuberculosis
is regarded as one of the most effective treatment options to shorten drug administration regimes, and reduce the opportunity for the emergence of drug resistance. During infection and pr...

Alternative Titles

Full title

The cryo-EM structure of the bd oxidase from M. tuberculosis reveals a unique structural framework and enables rational drug design to combat TB

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_d59d3dd24560451195a1764a95c9ea6d

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d59d3dd24560451195a1764a95c9ea6d

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-021-25537-z

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