A ChIP on the shoulder? Chromatin immunoprecipitation and validation strategies for ChIP antibodies...
A ChIP on the shoulder? Chromatin immunoprecipitation and validation strategies for ChIP antibodies [version 1; peer review: 2 approved]
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Publisher
England: F1000Research
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Language
English
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Publisher
England: F1000Research
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Contents
Chromatin immunoprecipitation (ChIP) is a technique widely used in the study of epigenetics and transcriptional regulation of gene expression. However, its antibody-centric nature exposes it to similar challenges faced by other antibody-based procedures, of which the most prominent are issues of specificity and affinity in antigen recognition. As w...
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Full title
A ChIP on the shoulder? Chromatin immunoprecipitation and validation strategies for ChIP antibodies [version 1; peer review: 2 approved]
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TN_cdi_doaj_primary_oai_doaj_org_article_d5bf02ab25c549918d10650229f4c5d2
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d5bf02ab25c549918d10650229f4c5d2
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ISSN
2046-1402
E-ISSN
2046-1402
DOI
10.12688/f1000research.6719.1
