Interfering B cell receptor signaling via SHP-1/p-Lyn axis shows therapeutic potential in diffuse la...
Interfering B cell receptor signaling via SHP-1/p-Lyn axis shows therapeutic potential in diffuse large B-cell lymphoma
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New York: Springer
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Language
English
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New York: Springer
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Background Diffuse large B cell lymphoma (DLBCL) is an aggressive and molecularly heterogeneous non-Hodgkin's lymphoma. The B cell receptor (BCR) signaling pathway in DLBCL emerges as a new drug target. Protein phosphatase SHP-1 negatively regulates several oncogenic tyrosine kinases and plays a tumor suppressive role. Methods The direct SHP-1 agon...
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Interfering B cell receptor signaling via SHP-1/p-Lyn axis shows therapeutic potential in diffuse large B-cell lymphoma
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TN_cdi_doaj_primary_oai_doaj_org_article_d5ce200f0c8547a79007dd9f9fcc3b5d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d5ce200f0c8547a79007dd9f9fcc3b5d
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ISSN
1076-1551
E-ISSN
1528-3658
DOI
10.1186/s10020-022-00518-0
