Molecular Dynamics of Cobalt Protoporphyrin Antagonism of the Cancer Suppressor REV-ERBβ
Molecular Dynamics of Cobalt Protoporphyrin Antagonism of the Cancer Suppressor REV-ERBβ
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Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Nuclear receptor REV-ERBβ is an overexpressed oncoprotein that has been used as a target for cancer treatment. The metal-complex nature of its ligand, iron protoporphyrin IX (Heme), enables the REV-ERBβ to be used for multiple therapeutic modalities as a photonuclease, a photosensitizer, or a fluorescence imaging agent. The replacement of iron with...
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Molecular Dynamics of Cobalt Protoporphyrin Antagonism of the Cancer Suppressor REV-ERBβ
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TN_cdi_doaj_primary_oai_doaj_org_article_d5cfab69eeaa4a99a8dcd40560f277f2
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d5cfab69eeaa4a99a8dcd40560f277f2
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ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules26113251
