CARM1-expressing ovarian cancer depends on the histone methyltransferase EZH2 activity
CARM1-expressing ovarian cancer depends on the histone methyltransferase EZH2 activity
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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CARM1 is an arginine methyltransferase that asymmetrically dimethylates protein substrates on arginine residues. CARM1 is often overexpressed in human cancers. However, clinically applicable cancer therapeutic strategies based on CARM1 expression remain to be explored. Here, we report that EZH2 inhibition is effective in CARM1-expressing epithelial...
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Full title
CARM1-expressing ovarian cancer depends on the histone methyltransferase EZH2 activity
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TN_cdi_doaj_primary_oai_doaj_org_article_d5feab71b5d34b35b80ea5240b6980bc
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d5feab71b5d34b35b80ea5240b6980bc
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-03031-3
