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The ISG15-Protease USP18 Is a Pleiotropic Enhancer of HIV-1 Replication

The ISG15-Protease USP18 Is a Pleiotropic Enhancer of HIV-1 Replication

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d61ad8202dbc47cdb8a67919f391ea8f

The ISG15-Protease USP18 Is a Pleiotropic Enhancer of HIV-1 Replication

About this item

Full title

The ISG15-Protease USP18 Is a Pleiotropic Enhancer of HIV-1 Replication

Publisher

Switzerland: MDPI AG

Journal title

Viruses, 2024-03, Vol.16 (4), p.485

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

The innate immune response to viruses is formed in part by interferon (IFN)-induced restriction factors, including ISG15, p21, and SAMHD1. IFN production can be blocked by the ISG15-specific protease USP18. HIV-1 has evolved to circumvent host immune surveillance. This mechanism might involve USP18. In our recent studies, we demonstrate that HIV-1...

Alternative Titles

Full title

The ISG15-Protease USP18 Is a Pleiotropic Enhancer of HIV-1 Replication

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_d61ad8202dbc47cdb8a67919f391ea8f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d61ad8202dbc47cdb8a67919f391ea8f

Other Identifiers

ISSN

1999-4915

E-ISSN

1999-4915

DOI

10.3390/v16040485

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