A STAT3-based gene signature stratifies glioma patients for targeted therapy
A STAT3-based gene signature stratifies glioma patients for targeted therapy
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London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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Intratumoral heterogeneity is a hallmark of glioblastoma (GBM) tumors, thought to negatively influence therapeutic outcome. Previous studies showed that mesenchymal tumors have a worse outcome than the proneural subtype. Here we focus on STAT3 as its activation precedes the proneural-mesenchymal transition. We first establish a
STAT3
gene sig...
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Full title
A STAT3-based gene signature stratifies glioma patients for targeted therapy
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TN_cdi_doaj_primary_oai_doaj_org_article_d61c46f20a3c44179f855b1383771751
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d61c46f20a3c44179f855b1383771751
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-11614-x
