KDM6B is an androgen regulated gene and plays oncogenic roles by demethylating H3K27me3 at cyclin D1...
KDM6B is an androgen regulated gene and plays oncogenic roles by demethylating H3K27me3 at cyclin D1 promoter in prostate cancer
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Cao, Zhi , Shi, Xiaolei , Tian, Feng , Fang, Yu , Wu, Jason Boyang , Mrdenovic, Stefan , Nian, Xinwen , Ji, Jin , Xu, Huan , Kong, Chen , Xu, Yalong , Chen, Xi , Huang, Yuhua , Wei, Xuedong , Yu, Yongwei , Yang, Bo , Chung, Leland W. K. and Wang, Fubo
Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Lysine (K)-specific demethylase 6B (KDM6B), a stress-inducible H3K27me3 demethylase, plays oncogenic or antitumoral roles in malignant tumors depending on the type of tumor cell. However, how this histone modifier affects the progression of prostate cancer (PCa) is still unknown. Here we analyzed sequenced gene expression data and tissue microarray...
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KDM6B is an androgen regulated gene and plays oncogenic roles by demethylating H3K27me3 at cyclin D1 promoter in prostate cancer
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TN_cdi_doaj_primary_oai_doaj_org_article_d638d6981b494bdf804b0c1b96a7bb4f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d638d6981b494bdf804b0c1b96a7bb4f
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-020-03354-4
