A versatile drug delivery system targeting senescent cells
A versatile drug delivery system targeting senescent cells
About this item
Full title
Author / Creator
Muñoz‐Espín, Daniel , Rovira, Miguel , Galiana, Irene , Giménez, Cristina , Lozano‐Torres, Beatriz , Paez‐Ribes, Marta , Llanos, Susana , Chaib, Selim , Muñoz‐Martín, Maribel , Ucero, Alvaro C , Garaulet, Guillermo , Mulero, Francisca , Dann, Stephen G , VanArsdale, Todd , Shields, David J , Bernardos, Andrea , Murguía, José Ramón , Martínez‐Máñez, Ramón and Serrano, Manuel
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Senescent cells accumulate in multiple aging‐associated diseases, and eliminating these cells has recently emerged as a promising therapeutic approach. Here, we take advantage of the high lysosomal β‐galactosidase activity of senescent cells to design a drug delivery system based on the encapsulation of drugs with galacto‐oligosaccharides. We show...
Alternative Titles
Full title
A versatile drug delivery system targeting senescent cells
Authors, Artists and Contributors
Author / Creator
Rovira, Miguel
Galiana, Irene
Giménez, Cristina
Lozano‐Torres, Beatriz
Paez‐Ribes, Marta
Llanos, Susana
Chaib, Selim
Muñoz‐Martín, Maribel
Ucero, Alvaro C
Garaulet, Guillermo
Mulero, Francisca
Dann, Stephen G
VanArsdale, Todd
Shields, David J
Bernardos, Andrea
Murguía, José Ramón
Martínez‐Máñez, Ramón
Serrano, Manuel
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_d67df62499c14123a2c81e830cc433e4
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d67df62499c14123a2c81e830cc433e4
Other Identifiers
ISSN
1757-4676,1757-4684
E-ISSN
1757-4684
DOI
10.15252/emmm.201809355
