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A short translational ramp determines the efficiency of protein synthesis

A short translational ramp determines the efficiency of protein synthesis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d6c7739bcd3d4753818faecc0bc65dc2

A short translational ramp determines the efficiency of protein synthesis

About this item

Full title

A short translational ramp determines the efficiency of protein synthesis

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2019-12, Vol.10 (1), p.5774-15, Article 5774

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Translation initiation is a major rate-limiting step for protein synthesis. However, recent studies strongly suggest that the efficiency of protein synthesis is additionally regulated by multiple factors that impact the elongation phase. To assess the influence of early elongation on protein synthesis, we employed a library of more than 250,000 rep...

Alternative Titles

Full title

A short translational ramp determines the efficiency of protein synthesis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_d6c7739bcd3d4753818faecc0bc65dc2

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d6c7739bcd3d4753818faecc0bc65dc2

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-019-13810-1

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