Neutrophil extracellular trap formation requires OPA1-dependent glycolytic ATP production
Neutrophil extracellular trap formation requires OPA1-dependent glycolytic ATP production
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Optic atrophy 1 (OPA1) is a mitochondrial inner membrane protein that has an important role in mitochondrial fusion and structural integrity. Dysfunctional OPA1 mutations cause atrophy of the optic nerve leading to blindness. Here, we show that OPA1 has an important role in the innate immune system. Using conditional knockout mice lacking Opa1 in n...
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Neutrophil extracellular trap formation requires OPA1-dependent glycolytic ATP production
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TN_cdi_doaj_primary_oai_doaj_org_article_d6d65756387f4a38a5e16d6f0ce5f658
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d6d65756387f4a38a5e16d6f0ce5f658
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-05387-y
