Habenular expression of rare missense variants of the β4 nicotinic receptor subunit alters nicotine...
Habenular expression of rare missense variants of the β4 nicotinic receptor subunit alters nicotine consumption
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Switzerland: Frontiers Research Foundation
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English
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Switzerland: Frontiers Research Foundation
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The CHRNA5-CHRNA3-CHRNB4 gene cluster, encoding the α5, α3, and β4 nicotinic acetylcholine receptor (nAChR) subunits, has been linked to nicotine dependence. The habenulo-interpeduncular (Hb-IPN) tract is particularly enriched in α3β4 nAChRs. We recently showed that modulation of these receptors in the medial habenula (MHb) in mice altered nicotine...
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Full title
Habenular expression of rare missense variants of the β4 nicotinic receptor subunit alters nicotine consumption
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TN_cdi_doaj_primary_oai_doaj_org_article_d6e084e02a3749ca99ab6d3e18d55095
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d6e084e02a3749ca99ab6d3e18d55095
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ISSN
1662-5161
E-ISSN
1662-5161
DOI
10.3389/fnhum.2014.00012
