Skeletal muscle stem cells modulate niche function in Duchenne muscular dystrophy mouse through YY1-...
Skeletal muscle stem cells modulate niche function in Duchenne muscular dystrophy mouse through YY1-CCL5 axis
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Author / Creator
Li, Yang , Li, Chuhan , Sun, Qiang , Liu, Xingyuan , Chen, Fengyuan , Cheung, Yeelo , Zhao, Yu , Xie, Ting , Chazaud, Bénédicte , Sun, Hao and Wang, Huating
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Adult skeletal muscle stem cells (MuSCs) are indispensable for muscle regeneration and tightly regulated by macrophages (MPs) and fibro-adipogenic progenitors (FAPs) in their niche. Deregulated MuSC/MP/FAP interactions and the ensuing inflammation and fibrosis are hallmarks of dystrophic muscle. Here we demonstrate intrinsic deletion of transcripti...
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Full title
Skeletal muscle stem cells modulate niche function in Duchenne muscular dystrophy mouse through YY1-CCL5 axis
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TN_cdi_doaj_primary_oai_doaj_org_article_d6e4122a29e04b9bb7998db3263e3415
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d6e4122a29e04b9bb7998db3263e3415
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-025-56474-w