Lycopene alleviates 5-fluorouracil-induced nephrotoxicity by modulating PPAR-γ, Nrf2/HO-1, and NF-κB...
Lycopene alleviates 5-fluorouracil-induced nephrotoxicity by modulating PPAR-γ, Nrf2/HO-1, and NF-κB/TNF-α/IL-6 signals
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England: Taylor & Francis Ltd
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English
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England: Taylor & Francis Ltd
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5-Fluorouracil (5-FU) is one of the most used anticancer drugs. However, its nephrotoxicity-associated drawback is of clinical concern. Lycopene (LYC) is a red carotenoid with remarkable anti-inflammatory and anti-oxidative properties. In this study, rats were divided randomly into five groups: control, lycopene (10 mg) (10 mg/kg/day; P.O), 5-FU (3...
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Full title
Lycopene alleviates 5-fluorouracil-induced nephrotoxicity by modulating PPAR-γ, Nrf2/HO-1, and NF-κB/TNF-α/IL-6 signals
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TN_cdi_doaj_primary_oai_doaj_org_article_d720a68a34cb470cbbe8b7cf6b26653f
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d720a68a34cb470cbbe8b7cf6b26653f
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ISSN
0886-022X,1525-6049
E-ISSN
1525-6049
DOI
10.1080/0886022X.2024.2423843
