Yeast-produced RBD-based recombinant protein vaccines elicit broadly neutralizing antibodies and dur...
Yeast-produced RBD-based recombinant protein vaccines elicit broadly neutralizing antibodies and durable protective immunity against SARS-CoV-2 infection
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Author / Creator
Zang, Jinkai , Zhu, Yuanfei , Zhou, Yu , Gu, Chenjian , Yi, Yufang , Wang, Shuxia , Xu, Shiqi , Hu, Gaowei , Du, Shujuan , Yin, Yannan , Wang, Yalei , Yang, Yong , Zhang, Xueyang , Wang, Haikun , Yin, Feifei , Zhang, Chao , Deng, Qiang , Xie, Youhua and Huang, Zhong
Publisher
Singapore: Springer Singapore
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Language
English
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Publisher
Singapore: Springer Singapore
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Scope and Contents
Contents
Massive production of efficacious SARS-CoV-2 vaccines is essential for controlling the ongoing COVID-19 pandemic. We report here the preclinical development of yeast-produced receptor-binding domain (RBD)-based recombinant protein SARS-CoV-2 vaccines. We found that monomeric RBD of SARS-CoV-2 could be efficiently produced as a secreted protein from...
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Full title
Yeast-produced RBD-based recombinant protein vaccines elicit broadly neutralizing antibodies and durable protective immunity against SARS-CoV-2 infection
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_d73624f8986a4196a53c8a1e4e16a49f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d73624f8986a4196a53c8a1e4e16a49f
Other Identifiers
ISSN
2056-5968
E-ISSN
2056-5968
DOI
10.1038/s41421-021-00315-9
