Calpain-mediated proteolysis as driver and modulator of polyglutamine toxicity
Calpain-mediated proteolysis as driver and modulator of polyglutamine toxicity
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Publisher
Lausanne: Frontiers Research Foundation
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Language
English
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Publisher
Lausanne: Frontiers Research Foundation
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Contents
Among posttranslational modifications, directed proteolytic processes have the strongest impact on protein integrity. They are executed by a variety of cellular machineries and lead to a wide range of molecular consequences. Compared to other forms of proteolytic enzymes, the class of calcium-activated calpains is considered as modulator proteases...
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Full title
Calpain-mediated proteolysis as driver and modulator of polyglutamine toxicity
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TN_cdi_doaj_primary_oai_doaj_org_article_d73f02fd395b4896a1b7ffd8fc9ceb68
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d73f02fd395b4896a1b7ffd8fc9ceb68
Other Identifiers
ISSN
1662-5099
E-ISSN
1662-5099
DOI
10.3389/fnmol.2022.1020104
