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Effects of rituximab in two patients with dysferlin-deficient muscular dystrophy

Effects of rituximab in two patients with dysferlin-deficient muscular dystrophy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d74f0867cea7416aba7438806326a5b7

Effects of rituximab in two patients with dysferlin-deficient muscular dystrophy

About this item

Full title

Effects of rituximab in two patients with dysferlin-deficient muscular dystrophy

Publisher

England: BioMed Central Ltd

Journal title

BMC musculoskeletal disorders, 2010-07, Vol.11 (1), p.157-157, Article 157

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

The administration of rituximab (RTX) in vivo results in B-cell depletion, but evidence for multiple mechanisms of action have been reported. Surprisingly, B cell depletion produced a response in patients with polymyositis, which is characterized as a T cell-mediated autoimmune disorder with biopsy findings similar to Miyoshi myopathy (MM). Indeed,...

Alternative Titles

Full title

Effects of rituximab in two patients with dysferlin-deficient muscular dystrophy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_d74f0867cea7416aba7438806326a5b7

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d74f0867cea7416aba7438806326a5b7

Other Identifiers

ISSN

1471-2474

E-ISSN

1471-2474

DOI

10.1186/1471-2474-11-157

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