Kupffer cells determine intrahepatic traffic of PEGylated liposomal doxorubicin
Kupffer cells determine intrahepatic traffic of PEGylated liposomal doxorubicin
About this item
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Author / Creator
Jiang, Kuan , Tian, Kaisong , Yu, Yifei , Wu, Ercan , Yang, Min , Pan, Feng , Qian, Jun and Zhan, Changyou
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Intrahepatic accumulation dominates organ distribution for most nanomedicines. However, obscure intrahepatic fate largely hampers regulation on their in vivo performance. Herein, PEGylated liposomal doxorubicin is exploited to clarify the intrahepatic fate of both liposomes and the payload in male mice. Kupffer cells initiate and dominate intrahepa...
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Full title
Kupffer cells determine intrahepatic traffic of PEGylated liposomal doxorubicin
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_d781b2f2daa64ebfa45b98ae2cc299e0
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d781b2f2daa64ebfa45b98ae2cc299e0
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-50568-7
