A nucleoid-associated protein is involved in the emergence of antibiotic resistance by promoting the...
A nucleoid-associated protein is involved in the emergence of antibiotic resistance by promoting the frequent exchange of the replicative DNA polymerase in Mycobacterium smegmatis
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United States: American Society for Microbiology
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Language
English
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Publisher
United States: American Society for Microbiology
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Contents
Unlike many other pathogens,
Mycobacterium tuberculosis
has limited ability for horizontal gene transfer, a major mechanism for developing antibiotic resistance. Thus, the mechanisms that facilitate chromosomal mutagenesis are of particular importance in mycobacteria. Here, we show that Lsr2, a nucleoid-associated protein, has a novel role in...
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Full title
A nucleoid-associated protein is involved in the emergence of antibiotic resistance by promoting the frequent exchange of the replicative DNA polymerase in Mycobacterium smegmatis
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TN_cdi_doaj_primary_oai_doaj_org_article_d808c4e477ee412eaca1e0cdf6d11376
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d808c4e477ee412eaca1e0cdf6d11376
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ISSN
2379-5042
E-ISSN
2379-5042
DOI
10.1128/msphere.00122-24
