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Thymidine kinase 1 concentration and activity in metastatic breast cancer under CDK4/6 inhibitor the...

Thymidine kinase 1 concentration and activity in metastatic breast cancer under CDK4/6 inhibitor the...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d83cbfbe70f248e7ab263ec1cc613c5a

Thymidine kinase 1 concentration and activity in metastatic breast cancer under CDK4/6 inhibitor therapy

About this item

Full title

Thymidine kinase 1 concentration and activity in metastatic breast cancer under CDK4/6 inhibitor therapy

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2025-03, Vol.15 (1), p.10347-15, Article 10347

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

We investigated whether TK1 concentration or activity in the blood, drawn at baseline and under therapy, might have value for therapy management in 110 hormone receptor-positive (HR+), HER2-negative (HER2-) metastatic breast cancer (mBC) patients treated with CDK4/6 inhibitors (CDK4/6i) and/or endocrine therapy (ET). TK1 concentration and activity...

Alternative Titles

Full title

Thymidine kinase 1 concentration and activity in metastatic breast cancer under CDK4/6 inhibitor therapy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_d83cbfbe70f248e7ab263ec1cc613c5a

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d83cbfbe70f248e7ab263ec1cc613c5a

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-025-95114-7

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