Skeletal muscle regeneration failure in ischemic-damaged limbs is associated with pro-inflammatory m...
Skeletal muscle regeneration failure in ischemic-damaged limbs is associated with pro-inflammatory macrophages and premature differentiation of satellite cells
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Chronic limb-threatening ischemia (CLTI), a severe manifestation of peripheral arterial disease (PAD), is associated with a 1-year limb amputation rate of approximately 15-20% and substantial mortality. A key feature of CLTI is the compromised regenerative ability of skeletal muscle; however, the mechanisms responsible for this impairment are not y...
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Full title
Skeletal muscle regeneration failure in ischemic-damaged limbs is associated with pro-inflammatory macrophages and premature differentiation of satellite cells
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TN_cdi_doaj_primary_oai_doaj_org_article_d8791787c9d54c2aab08d00540e6d0a0
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d8791787c9d54c2aab08d00540e6d0a0
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ISSN
1756-994X
E-ISSN
1756-994X
DOI
10.1186/s13073-023-01250-y
