A scalable, clinically severe pig model for Duchenne muscular dystrophy
A scalable, clinically severe pig model for Duchenne muscular dystrophy
About this item
Full title
Author / Creator
Stirm, Michael , Fonteyne, Lina Marie , Shashikadze, Bachuki , Lindner, Magdalena , Chirivi, Maila , Lange, Andreas , Kaufhold, Clara , Mayer, Christian , Medugorac, Ivica , Kessler, Barbara , Kurome, Mayuko , Zakhartchenko, Valeri , Hinrichs, Arne , Kemter, Elisabeth , Krause, Sabine , Wanke, Rüdiger , Arnold, Georg J. , Wess, Gerhard , Nagashima, Hiroshi , Hrabĕ de Angelis, Martin , Flenkenthaler, Florian , Kobelke, Levin Arne , Bearzi, Claudia , Rizzi, Roberto , Bähr, Andrea , Reese, Sven , Matiasek, Kaspar , Walter, Maggie C. , Kupatt, Christian , Ziegler, Sibylle , Bartenstein, Peter , Fröhlich, Thomas , Klymiuk, Nikolai , Blutke, Andreas and Wolf, Eckhard
Publisher
England: The Company of Biologists Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: The Company of Biologists Ltd
Subjects
More information
Scope and Contents
Contents
Large-animal models for Duchenne muscular dystrophy (DMD) are crucial for the evaluation of diagnostic procedures and treatment strategies. Pigs cloned from male cells lacking DMD exon 52 (DMDΔ52) exhibit molecular, clinical and pathological hallmarks of DMD, but die before sexual maturity and cannot be propagated by breeding. Therefore, we generat...
Alternative Titles
Full title
A scalable, clinically severe pig model for Duchenne muscular dystrophy
Authors, Artists and Contributors
Author / Creator
Fonteyne, Lina Marie
Shashikadze, Bachuki
Lindner, Magdalena
Chirivi, Maila
Lange, Andreas
Kaufhold, Clara
Mayer, Christian
Medugorac, Ivica
Kessler, Barbara
Kurome, Mayuko
Zakhartchenko, Valeri
Hinrichs, Arne
Kemter, Elisabeth
Krause, Sabine
Wanke, Rüdiger
Arnold, Georg J.
Wess, Gerhard
Nagashima, Hiroshi
Hrabĕ de Angelis, Martin
Flenkenthaler, Florian
Kobelke, Levin Arne
Bearzi, Claudia
Rizzi, Roberto
Bähr, Andrea
Reese, Sven
Matiasek, Kaspar
Walter, Maggie C.
Kupatt, Christian
Ziegler, Sibylle
Bartenstein, Peter
Fröhlich, Thomas
Klymiuk, Nikolai
Blutke, Andreas
Wolf, Eckhard
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_d8939e99103646a0a9090e1ac2200524
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d8939e99103646a0a9090e1ac2200524
Other Identifiers
ISSN
1754-8403
E-ISSN
1754-8411
DOI
10.1242/dmm.049285
