A cleaved METTL3 potentiates the METTL3–WTAP interaction and breast cancer progression
A cleaved METTL3 potentiates the METTL3–WTAP interaction and breast cancer progression
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Cambridge: eLife Science Publications, Ltd
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Language
English
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Publisher
Cambridge: eLife Science Publications, Ltd
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Contents
N
6
-methyladenosine (m
6
A) methylation of RNA by the methyltransferase complex (MTC), with core components including METTL3–METTL14 heterodimers and
Wilms’ tumor 1-associated protein
(WTAP), contributes to breast tumorigenesis, but the underlying regulatory mechanisms remain elusive. Here, we identify a novel cleaved form METTL3...
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Full title
A cleaved METTL3 potentiates the METTL3–WTAP interaction and breast cancer progression
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TN_cdi_doaj_primary_oai_doaj_org_article_d8a43705d24e475c9588915e832d39a2
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d8a43705d24e475c9588915e832d39a2
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.87283
