156 Discovery of TSC-100: A natural HA-1-specific TCR to treat leukemia following hematopoietic stem...
156 Discovery of TSC-100: A natural HA-1-specific TCR to treat leukemia following hematopoietic stem cell transplant therapy
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Author / Creator
Nayar, Ribhu , Jangalwe, Sonal , Jurewicz, Mollie , Boudot, Antoine , Basinski, Andrew , Prenovitz, Robert , Olesin, Elizabeth , Pollacksmith, Daniel , Xu, Qikai , Wang, Yifan , Virbasius, Amy , Li, Jeffery , Whitton, Holly , Dunlap, Garrett , Cristofaro, Alexander , Nabilsi, Nancy , Zhang, Ruan , Perullo, Candace , Liao, Sida , Jahan, Kenneth , Olivier, Kenneth and MacBeath, Gavin
Publisher
London: BMJ Publishing Group LTD
Journal title
Language
English
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Publisher
London: BMJ Publishing Group LTD
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Contents
BackgroundApproximately 30–40% of AML patients relapse following allogeneic hematopoietic stem cell transplant therapy, leaving them with very few treatment options.1 2 Rare patients that naturally develop an HA-1-specific graft-versus-leukemia T cell response, however, show substantially lower relapse rates.3 4 HA-1 (VLHDDLLEA, genotype RS_1801284...
Alternative Titles
Full title
156 Discovery of TSC-100: A natural HA-1-specific TCR to treat leukemia following hematopoietic stem cell transplant therapy
Authors, Artists and Contributors
Author / Creator
Jangalwe, Sonal
Jurewicz, Mollie
Boudot, Antoine
Basinski, Andrew
Prenovitz, Robert
Olesin, Elizabeth
Pollacksmith, Daniel
Xu, Qikai
Wang, Yifan
Virbasius, Amy
Li, Jeffery
Whitton, Holly
Dunlap, Garrett
Cristofaro, Alexander
Nabilsi, Nancy
Zhang, Ruan
Perullo, Candace
Liao, Sida
Jahan, Kenneth
Olivier, Kenneth
MacBeath, Gavin
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_d8b81dd10b4b49dd8f55a003956d8da4
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d8b81dd10b4b49dd8f55a003956d8da4
Other Identifiers
E-ISSN
2051-1426
DOI
10.1136/jitc-2020-SITC2020.0156