Adenosine receptor agonism protects against NETosis and thrombosis in antiphospholipid syndrome
Adenosine receptor agonism protects against NETosis and thrombosis in antiphospholipid syndrome
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Potentiation of neutrophil extracellular trap (NET) release is one mechanism by which antiphospholipid antibodies (aPL Abs) effect thrombotic events in patients with antiphospholipid syndrome (APS). Surface adenosine receptors trigger cyclic AMP (cAMP) formation in neutrophils, and this mechanism has been proposed to regulate NETosis in some contex...
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Adenosine receptor agonism protects against NETosis and thrombosis in antiphospholipid syndrome
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TN_cdi_doaj_primary_oai_doaj_org_article_d8ca98b7f1d54784a2dbed7642ccb42a
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d8ca98b7f1d54784a2dbed7642ccb42a
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-09801-x
