Senescent-like microglia limit remyelination through the senescence associated secretory phenotype
Senescent-like microglia limit remyelination through the senescence associated secretory phenotype
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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The capacity to regenerate myelin in the central nervous system diminishes with age. This decline is particularly evident in multiple sclerosis (MS), a chronic demyelinating disease. Whether cellular senescence, a hallmark of aging, contributes to remyelination impairment remains unknown. Here, we show that senescent cells accumulate within demyeli...
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Senescent-like microglia limit remyelination through the senescence associated secretory phenotype
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TN_cdi_doaj_primary_oai_doaj_org_article_d8cbf7d37ca041ab8fe28fc270cd675f
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d8cbf7d37ca041ab8fe28fc270cd675f
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-025-57632-w
