Conformational dynamics of a nicotinic receptor neurotransmitter site
Conformational dynamics of a nicotinic receptor neurotransmitter site
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England: eLife Science Publications, Ltd
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English
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Publisher
England: eLife Science Publications, Ltd
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Agonists enhance receptor activity by providing net-favorable binding energy to active over resting conformations, with efficiency (η) linking binding energy to gating. Previously, we showed that in nicotinic receptors, η-values are grouped into five structural pairs, correlating efficacy and affinity within each class, uniting binding with alloste...
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Full title
Conformational dynamics of a nicotinic receptor neurotransmitter site
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TN_cdi_doaj_primary_oai_doaj_org_article_d8d6d6a370fa4ab58f2e2f8a22bd7eee
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d8d6d6a370fa4ab58f2e2f8a22bd7eee
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.92418
