The canonical TGF-β/Smad signalling pathway is involved in PD-L1-induced primary resistance to EGFR-...
The canonical TGF-β/Smad signalling pathway is involved in PD-L1-induced primary resistance to EGFR-TKIs in EGFR-mutant non-small-cell lung cancer
About this item
Full title
Author / Creator
Zhang, Yang , Zeng, Yuanyuan , Liu, Ting , Du, Wenwen , Zhu, Jianjie , Liu, Zeyi and Huang, Jian-An
Publisher
England: BioMed Central
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central
Subjects
More information
Scope and Contents
Contents
Approximately 30% of patients with epidermal growth factor receptor (EGFR)-activating mutations have no response to EGFR-tyrosine kinase inhibitors (TKIs) (primary resistance). However, little is known about the molecular mechanism involved in primary resistance to EGFR-TKIs in EGFR-mutant non-small cell lung cancer (NSCLC). Programmed death ligand...
Alternative Titles
Full title
The canonical TGF-β/Smad signalling pathway is involved in PD-L1-induced primary resistance to EGFR-TKIs in EGFR-mutant non-small-cell lung cancer
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_d913bc33bc2b45bcb24a9324e5171b7c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d913bc33bc2b45bcb24a9324e5171b7c
Other Identifiers
ISSN
1465-993X,1465-9921
E-ISSN
1465-993X
DOI
10.1186/s12931-019-1137-4
