Overexpression of miR-21 in stem cells improves ovarian structure and function in rats with chemothe...
Overexpression of miR-21 in stem cells improves ovarian structure and function in rats with chemotherapy-induced ovarian damage by targeting PDCD4 and PTEN to inhibit granulosa cell apoptosis
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Chemotherapy-induced premature ovarian failure (POF) is a severe complication affecting tumor patients at a childbearing age. Mesenchymal stem cells (MSCs) can partially restore the ovarian structure and function damaged by chemotherapy. miR-21 is a microRNA that can regulate cell apoptosis. This study discusses the repair effect and mechanism of M...
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Full title
Overexpression of miR-21 in stem cells improves ovarian structure and function in rats with chemotherapy-induced ovarian damage by targeting PDCD4 and PTEN to inhibit granulosa cell apoptosis
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TN_cdi_doaj_primary_oai_doaj_org_article_d92baa6097fc4cbab3dc36e5e8cfd951
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d92baa6097fc4cbab3dc36e5e8cfd951
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ISSN
1757-6512
E-ISSN
1757-6512
DOI
10.1186/s13287-017-0641-z
