Micro-environmental sensing by bone marrow stroma identifies IL-6 and TGFβ1 as regulators of hematop...
Micro-environmental sensing by bone marrow stroma identifies IL-6 and TGFβ1 as regulators of hematopoietic ageing
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Hematopoietic ageing involves declining erythropoiesis and lymphopoiesis, leading to frequent anaemia and decreased adaptive immunity. How intrinsic changes to the hematopoietic stem cells (HSCs), an altered microenvironment and systemic factors contribute to this process is not fully understood. Here we use bone marrow stromal cells as sensors of...
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Micro-environmental sensing by bone marrow stroma identifies IL-6 and TGFβ1 as regulators of hematopoietic ageing
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TN_cdi_doaj_primary_oai_doaj_org_article_d92c05c8ae8e4f60abab394fce4e0c0b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d92c05c8ae8e4f60abab394fce4e0c0b
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-17942-7
