Role of the αC-β4 loop in protein kinase structure and dynamics
Role of the αC-β4 loop in protein kinase structure and dynamics
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England: eLife Sciences Publications, Ltd
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Language
English
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England: eLife Sciences Publications, Ltd
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Contents
Although the αC-β4 loop is a stable feature of all protein kinases, the importance of this motif as a conserved element of secondary structure, as well as its links to the hydrophobic architecture of the kinase core, has been underappreciated. We first review the motif and then describe how it is linked to the hydrophobic spine architecture of the...
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Full title
Role of the αC-β4 loop in protein kinase structure and dynamics
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TN_cdi_doaj_primary_oai_doaj_org_article_d95e3a9288ba4ee1888840bfdd411ffc
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d95e3a9288ba4ee1888840bfdd411ffc
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.91980
