An EHMT2/NFYA-ALDH2 signaling axis modulates the RAF pathway to regulate paclitaxel resistance in lu...
An EHMT2/NFYA-ALDH2 signaling axis modulates the RAF pathway to regulate paclitaxel resistance in lung cancer
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Author / Creator
Wang, Wenjing , Wang, Jianmin , Liu, Shuai , Ren, Yong , Wang, Jingyu , Liu, Sen , Cui, Wei , Jia, Lina , Tang, Xing , Yang, Jingyu , Wu, Chunfu and Wang, Lihui
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Lung cancer is a kind of malignancy with high morbidity and mortality worldwide. Paclitaxel (PTX) is the main treatment for non-small cell lung cancer (NSCLC), and resistance to PTX seriously affects the survival of patients. However, the underlying mechanism and potential reversing strategy need to be further explored.
We identified ALDH2 as a...
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Full title
An EHMT2/NFYA-ALDH2 signaling axis modulates the RAF pathway to regulate paclitaxel resistance in lung cancer
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_d9776c838d8c4a1b8953af030cd0a56a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d9776c838d8c4a1b8953af030cd0a56a
Other Identifiers
ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/s12943-022-01579-9
