Extensive accumulation of misfolded protein aggregates during natural aging and senescence
Extensive accumulation of misfolded protein aggregates during natural aging and senescence
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Publisher
Switzerland: Frontiers Research Foundation
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Language
English
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Publisher
Switzerland: Frontiers Research Foundation
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Contents
Accumulation of misfolded protein aggregates is a hallmark event in many age-related protein misfolding disorders, including some of the most prevalent and insidious neurodegenerative diseases. Misfolded protein aggregates produce progressive cell damage, organ dysfunction, and clinical changes, which are common also in natural aging. Thus, we hypo...
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Full title
Extensive accumulation of misfolded protein aggregates during natural aging and senescence
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TN_cdi_doaj_primary_oai_doaj_org_article_d984ca75325c4129a94b4880499a878b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d984ca75325c4129a94b4880499a878b
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ISSN
1663-4365
E-ISSN
1663-4365
DOI
10.3389/fnagi.2022.1090109
