Log in to save to my catalogue

Anesthesia promotes acute expression of genes related to Alzheimer’s disease and latent tau aggregat...

Anesthesia promotes acute expression of genes related to Alzheimer’s disease and latent tau aggregat...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d9b69ff470b8434ebfcc2e3bc0c6f3c8

Anesthesia promotes acute expression of genes related to Alzheimer’s disease and latent tau aggregation in transgenic mouse models of tauopathy

About this item

Full title

Anesthesia promotes acute expression of genes related to Alzheimer’s disease and latent tau aggregation in transgenic mouse models of tauopathy

Publisher

New York: Springer

Journal title

Molecular Medicine, 2022-07, Vol.28 (1), p.1-83, Article 83

Language

English

Formats

Publication information

Publisher

New York: Springer

More information

Scope and Contents

Contents

Background Exposure to anesthesia in the elderly might increase the risk of dementia. Although the mechanism underlying the association is uncertain, anesthesia has been shown to induce acute tau hyperphosphorylation in preclinical models. We sought to investigate the impact of anesthesia on gene expression and on acute and long-term changes in tau...

Alternative Titles

Full title

Anesthesia promotes acute expression of genes related to Alzheimer’s disease and latent tau aggregation in transgenic mouse models of tauopathy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_d9b69ff470b8434ebfcc2e3bc0c6f3c8

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_d9b69ff470b8434ebfcc2e3bc0c6f3c8

Other Identifiers

ISSN

1076-1551

E-ISSN

1528-3658

DOI

10.1186/s10020-022-00506-4

How to access this item