Engineered E. coli Nissle 1917 for the delivery of matrix-tethered therapeutic domains to the gut
Engineered E. coli Nissle 1917 for the delivery of matrix-tethered therapeutic domains to the gut
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Mucosal healing plays a critical role in combatting the effects of inflammatory bowel disease, fistulae and ulcers. While most treatments for such diseases focus on systemically delivered anti-inflammatory drugs, often leading to detrimental side effects, mucosal healing agents that target the gut epithelium are underexplored. We genetically engine...
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Full title
Engineered E. coli Nissle 1917 for the delivery of matrix-tethered therapeutic domains to the gut
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TN_cdi_doaj_primary_oai_doaj_org_article_da22cd1382ed4f4c88ee9a65f788efef
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_da22cd1382ed4f4c88ee9a65f788efef
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-13336-6
