Sulforaphane Inhibits Oxidative Stress and May Exert Anti-Pyroptotic Effects by Modulating NRF2/NLRP...
Sulforaphane Inhibits Oxidative Stress and May Exert Anti-Pyroptotic Effects by Modulating NRF2/NLRP3 Signaling Pathway in Mycobacterium tuberculosis-Infected Macrophages
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Chen, Guangxin , Shen, Lin , Hu, Hong , Feng, Yazhi , Wen, Da , Liu, Yiyao , Zhai, Huizhe , Sun, Wei , Wang, Meifen , Lei, Xinghua , Li, Ping , Xiong, Qiuhong and Wu, Changxin
Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Sulforaphane (SFN) is a natural isothiocyanate derived from cruciferous vegetables such as broccoli, Brussels sprouts, and cabbage. SFN plays a crucial role in maintaining redox homeostasis by interacting with the active cysteine residues of Keap1, leading to the dissociation and activation of NRF2 in various diseases. In this study, our objective...
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Full title
Sulforaphane Inhibits Oxidative Stress and May Exert Anti-Pyroptotic Effects by Modulating NRF2/NLRP3 Signaling Pathway in Mycobacterium tuberculosis-Infected Macrophages
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TN_cdi_doaj_primary_oai_doaj_org_article_da4361658188437ba77c485f88fa4fa3
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_da4361658188437ba77c485f88fa4fa3
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ISSN
2076-2607
E-ISSN
2076-2607
DOI
10.3390/microorganisms12061191
