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Blockade of adenosine A2A receptors prevents interleukin-1β-induced exacerbation of neuronal toxicit...

Blockade of adenosine A2A receptors prevents interleukin-1β-induced exacerbation of neuronal toxicit...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_da84f70ffa0a4c548c63471fa06f2091

Blockade of adenosine A2A receptors prevents interleukin-1β-induced exacerbation of neuronal toxicity through a p38 mitogen-activated protein kinase pathway

About this item

Full title

Blockade of adenosine A2A receptors prevents interleukin-1β-induced exacerbation of neuronal toxicity through a p38 mitogen-activated protein kinase pathway

Publisher

England: BioMed Central Ltd

Journal title

Journal of neuroinflammation, 2012-08, Vol.9 (1), p.204-204, Article 669

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Blockade of adenosine A(2A) receptors (A(2A)R) affords robust neuroprotection in a number of brain conditions, although the mechanisms are still unknown. A likely candidate mechanism for this neuroprotection is the control of neuroinflammation, which contributes to the amplification of neurodegeneration, mainly through the abnormal release of pro-i...

Alternative Titles

Full title

Blockade of adenosine A2A receptors prevents interleukin-1β-induced exacerbation of neuronal toxicity through a p38 mitogen-activated protein kinase pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_da84f70ffa0a4c548c63471fa06f2091

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_da84f70ffa0a4c548c63471fa06f2091

Other Identifiers

ISSN

1742-2094

E-ISSN

1742-2094

DOI

10.1186/1742-2094-9-204

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