A Clickable Oxysterol Photolabel Retains NMDA Receptor Activity and Accumulates in Neurons
A Clickable Oxysterol Photolabel Retains NMDA Receptor Activity and Accumulates in Neurons
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Switzerland: Frontiers Research Foundation
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Language
English
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Publisher
Switzerland: Frontiers Research Foundation
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Contents
Oxysterol analogs that modulate NMDA receptor function are candidates for therapeutic development to treat neuropsychiatric disorders. However, the cellular actions of these compounds are still unclear. For instance, how these compounds are compartmentalized or trafficked in neurons is unknown. In this study, we utilized a chemical biology approach...
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Full title
A Clickable Oxysterol Photolabel Retains NMDA Receptor Activity and Accumulates in Neurons
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TN_cdi_doaj_primary_oai_doaj_org_article_da8a6926823744cd98ab46013ac9204d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_da8a6926823744cd98ab46013ac9204d
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ISSN
1662-453X,1662-4548
E-ISSN
1662-453X
DOI
10.3389/fnins.2018.00923
