Non-coding variability at the APOE locus contributes to the Alzheimer’s risk
Non-coding variability at the APOE locus contributes to the Alzheimer’s risk
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Alzheimer’s disease (AD) is a leading cause of mortality in the elderly. While the coding change of
APOE
-ε4 is a key risk factor for late-onset AD and has been believed to be the only risk factor in the
APOE
locus, it does not fully explain the risk effect conferred by the locus. Here, we report the identification of AD causal variants...
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Full title
Non-coding variability at the APOE locus contributes to the Alzheimer’s risk
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TN_cdi_doaj_primary_oai_doaj_org_article_daea0c2091424966946bd2ca4738d8a4
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_daea0c2091424966946bd2ca4738d8a4
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-10945-z
