The sialidase NEU3 promotes pulmonary fibrosis in mice
The sialidase NEU3 promotes pulmonary fibrosis in mice
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London: BioMed Central Ltd
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English
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London: BioMed Central Ltd
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Background Sialic acid is often the distal sugar on glycoconjugates, and sialidases are enzymes that remove this sugar. In fibrotic lesions in human and mouse lungs, there is extensive desialylation of glycoconjugates, and upregulation of sialidases including the extracellular sialidase NEU3. In the bleomycin model of pulmonary fibrosis, mice lacki...
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The sialidase NEU3 promotes pulmonary fibrosis in mice
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TN_cdi_doaj_primary_oai_doaj_org_article_daede1f497744dc4b867b7f035d23b31
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_daede1f497744dc4b867b7f035d23b31
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ISSN
1465-993X,1465-9921
E-ISSN
1465-993X,1465-9921
DOI
10.1186/s12931-022-02146-y
