Hurdles to breakthrough in CAR T cell therapy of solid tumors
Hurdles to breakthrough in CAR T cell therapy of solid tumors
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Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Autologous T cells genetically engineered to express chimeric antigen receptor (CAR) have shown promising outcomes and emerged as a new curative option for hematological malignancy, especially malignant neoplasm of B cells. Notably, when T cells are transduced with CAR constructs, composed of the antigen recognition domain of monoclonal antibodies,...
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Full title
Hurdles to breakthrough in CAR T cell therapy of solid tumors
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TN_cdi_doaj_primary_oai_doaj_org_article_daf4ab2f82f54ece85cb18c1efcbcff7
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_daf4ab2f82f54ece85cb18c1efcbcff7
Other Identifiers
ISSN
1757-6512
E-ISSN
1757-6512
DOI
10.1186/s13287-022-02819-x
